Fig. 1 · Structure

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Orotidine 5′-monophosphate trisodium

Pyrimidine Nucleotide

Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide that serves as an essential precursor in the de novo synthesis pathway for nucleotides. It plays a critical role in DNA synthesis across various microorganisms, including M. tuberculosis, S. cerevisiae, S. typhimurium, and P. falciparum. The formation of orotidine 5'-monophosphate trisodium involves the enzymatic action of orotate phosphoribosyltransferase (OPRT), utilizing phosphoribosyl pyrophosphate (PRPP) and orotic acid as substrates. This compound is invaluable for research in molecular biology and microbiology.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 68244-58-6
Applications Pyrimidine Nucleotide
Formula C10H10N2Na3O11P
Molecular Weight 434.14
Synonyms Orotidine monophosphate trisodium; Orotidylic acid trisodium
SMILES
O=C(C(N([C@H]1[C@@H]([C@@H]([C@@H](COP(O[Na])(O[Na])=O)O1)O)O)C2=O)=CC(N2)=O)O[Na]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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