Oroxylin A

Catalog No.: A14367

Oroxylin A

Oroxylin A Chemical Structure

CAS NO. 480-11-5

Oroxylin A is an O-methylated flavone, It has demonstrated activity as a dopamine reuptake inhibitor and is also a negative allosteric modulator of the benzodiazepine site of the GABAA receptor.

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5 mg

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  • Mai Nagasaka, .et al. Anti-Tumorigenic Activity of Chrysin from Oroxylum indicum via Non-Genotoxic p53 Activation through the ATM-Chk2 Pathway, Molecules, 2018, Jun; 23(6): 1394 PMID: 29890668

Biological Activity

Oroxylin A is an O-methylated flavone, It has demonstrated activity as a dopamine reuptake inhibitor and is also a negative allosteric modulator of the benzodiazepine site of the GABAA receptor.
In vitro DMSO 53 mg/mL (186.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.18 mL 175.89 mL 351.78 mL
0.5 mM 7.04 mL 35.18 mL 70.36 mL
1 mM 3.52 mL 17.59 mL 35.18 mL
5 mM 0.7 mL 3.52 mL 7.04 mL

*The above data is based on the productmolecular weight 284.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14367
CAS No. 480-11-5
Formula C16H12O5
M. Wt 284.27
Purity >98%
Synonyms Oroxyline-A, OroxylinA
SMILES COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC=CC=C3)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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