Fig. 1 · Structure
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Orphanin FQ(1-11)
NOP/OP4 Receptor Agonist
Orphanin FQ(1-11) is a potent agonist of the NOP (nociceptin/orphanin FQ peptide) receptor, with a Ki value of 55 nM. This fragment exhibits selective activity, showing no affinity for μ, δ, κ1, or κ3 opioid receptors (Ki > 1000 nM). Orphanin FQ(1-11) has demonstrated analgesic effects in CD-1 mouse models, making it a valuable tool for studying pain modulation and the nociceptin system in various research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 178249-41-7 |
| Applications | NOP/OP4 Receptor Agonist |
| Formula | C49H75N15O14 |
| Molecular Weight | 1098.21 |
| SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CO)=O)CCCCN)=O)CCCNC(=N)N)=O)C)=O)=O)[C@@H](C)O)=O)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.