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OSI-413 free base

Erlotinib Metabolite

OSI-413 free base is a significant metabolite of Erlotinib, a potent EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. This compound is instrumental in studying Erlotinib's metabolic pathways and its pharmacological effects. OSI-413 may provide valuable insights into alternative mechanisms of action and resistance, making it a relevant tool for cancer research, particularly in contexts involving EGFR-targeted therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	183320-29-8
Applications	Erlotinib Metabolite
Formula	C₂₁H₂₁N₃O₄
Molecular Weight	379.41
Synonyms	CP 373413
SMILES	OCCOC1=C(OCCOC)C=C2C(N=CN=C2NC3=CC(C#C)=CC=C3)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.