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OSU-02067

PDK-1 Inhibitor

OSU-02067 is a selective inhibitor of 3-phosphoinositide-dependent protein kinase-1 (PDK-1), with an IC50 value of 9 μM. This compound demonstrates potential for the investigation of solid tumors, including prostate, breast, and colorectal cancers. Its ability to target PDK-1 makes it a valuable tool for elucidating the role of this kinase in cancer biology and therapeutic resistance.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	618068-98-7
Applications	PDK-1 Inhibitor
Formula	C₂₄H₁₆F₃N₃O₂S
Molecular Weight	467.46
SMILES	O=S(N)(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC(C=CC4=C5C=CC=C4)=C5C=C3)C=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.