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Otviciclib

CDK Inhibitor

Otviciclib is a potent cyclin-dependent kinase (CDK) inhibitor that demonstrates significant anti-proliferative effects against various solid tumor cell lines, including HCT116, NCIH82, and DU145. This compound effectively induces cell cycle arrest in the G2/M phase and triggers apoptosis, exhibiting a favorable toxicity profile towards normal cells. Otviciclib shows broad-spectrum anticancer activity, making it a valuable tool for research applications related to colon, pancreatic, and lung cancers.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2228039-87-8
Applications	CDK Inhibitor
Formula	C₂₆H₃₀Cl₂N₈O₄S
Molecular Weight	621.54
SMILES	O=C1N=C(CC2=CC=C(NC(CN(CC)CC)=O)C=C2)NC3=C1C(N(C)C)=NN3C4=C(C=C(S(=O)(N)=O)C=C4Cl)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.