Fig. 1 · Structure
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Oxaliplatin-d10
Stable Isotope
Oxaliplatin-d10 is a deuterium-labeled derivative of Oxaliplatin, an effective DNA synthesis inhibitor. Its primary mechanism involves the induction of DNA crosslinking, which disrupts DNA replication and transcription, ultimately leading to apoptosis in cancer cells. This stable isotope is valuable for cancer research, particularly in studies focused on drug metabolism and pharmacokinetics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1132819-16-9 |
| Applications | Stable Isotope |
| Formula | C8H4D10N2O4Pt |
| Molecular Weight | 407.35 |
| SMILES | O=C1[O-][Pt+2]2([O-]C1=O)[NH2][C@@]3([2H])[C@](C([2H])([2H])C([2H])([2H])C([2H])([2H])C3([2H])[2H])([2H])[NH2]2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.