Oxprenolol HCl

Catalog No.: A17368

Non-selective β antagonist

Oxprenolol HCl

Oxprenolol HCl Chemical Structure

CAS NO. 6452-73-9

Oxprenolol is an orally bioavailable β-adrenergic receptor (β-AR) antagonist (Ki = 7.10 nM in a radioligand binding assay using rat heart tissue). It is non-selective and inhibits both β1- and β2-ARs (Kds = 2.09 and 1.35 nM in isolated rat heart and uterus, respectively). Oxprenolol is selective for β-ARs over serotonin (5-HT) receptors in rat sarcolemmal membrane preparations (IC50s = 4.13 and 23,300 nM, respectively), but it binds to 5-HT1A receptors in rat hippocampus and 5-HT1B in rat striatum (Kis = 94.2 and 642 nM, respectively).

Availability: In stock

Package Price Qty
100 mg

Regular Price: $50.00

Special Price $40.00

500 mg

Regular Price: $200.00

Special Price $160.00

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Oxprenolol is an orally bioavailable β-adrenergic receptor (β-AR) antagonist (Ki = 7.10 nM in a radioligand binding assay using rat heart tissue). It is non-selective and inhibits both β1- and β2-ARs (Kds = 2.09 and 1.35 nM in isolated rat heart and uterus, respectively). Oxprenolol is selective for β-ARs over serotonin (5-HT) receptors in rat sarcolemmal membrane preparations (IC50s = 4.13 and 23,300 nM, respectively), but it binds to 5-HT1A receptors in rat hippocampus and 5-HT1B in rat striatum (Kis = 94.2 and 642 nM, respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.13 mL 165.67 mL 331.33 mL
0.5 mM 6.63 mL 33.13 mL 66.27 mL
1 mM 3.31 mL 16.57 mL 33.13 mL
5 mM 0.66 mL 3.31 mL 6.63 mL

*The above data is based on the productmolecular weight 301.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17368
Actions Antagonist
CAS No. 6452-73-9
Formula C15H24ClNO3
M. Wt 301.81
Purity >98%
Synonyms Oxprenolol hydrochloride; Coretal; Dialicor; Rixiprol; Trasicor; Evinrozit; Ranidrox; Oxprenolol HCl; Trepress; Vrachor; Ba 39089; Ba-39089; Ba39089
SMILES OC(CNC(C)C)COC1=CC=CC=C1OCC=C.[H]Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Oxprenolol HCl | Oxprenolol HCl Supplier | purchase | cost | manufacturer | order | distributor | buy 6452-73-9| 6452-73-9 Supplier | purchase 6452-73-9 | 6452-73-9 cost | 6452-73-9 manufacturer | order 6452-73-9 | 6452-73-9 distributor
Rewards