Oxymatrine-d3 is a deuterium-labeled derivative of Oxymatrine, an alkaloid extracted from Sophora flavescens with notable anti-inflammatory, antifibrotic, and antitumor properties. It primarily targets the inhibition of inducible nitric oxide synthase (iNOS) expression and disrupts the TGF-β/Smad signaling pathway. Oxymatrine-d3 is useful in research applications focused on viral pathogenesis, demonstrating efficacy in inhibiting the replication of minute virus of canines (MVC) and reducing associated viral gene expression while mitigating apoptosis resulting from viral infections.
Oxymatrine-d3 is a deuterium-labeled derivative of Oxymatrine, an alkaloid extracted from Sophora flavescens with notable anti-inflammatory, antifibrotic, and antitumor properties. It primarily targets the inhibition of inducible nitric oxide synthase (iNOS) expression and disrupts the TGF-β/Smad signaling pathway. Oxymatrine-d3 is useful in research applications focused on viral pathogenesis, demonstrating efficacy in inhibiting the replication of minute virus of canines (MVC) and reducing associated viral gene expression while mitigating apoptosis resulting from viral infections.
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