Fig. 1 · Structure

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OZO-Cl

GST Inhibitor

OZO-Cl is a potent inhibitor of glutathione S-transferase (GST), primarily targeting the Pi isoform. This compound demonstrates significant anti-cancer activity, exhibiting cytotoxic effects on various cancer cell lines with IC50 values of 150 μmol/L in Panc-1 and 120 μmol/L in K562 cells. OZO-Cl may serve as a valuable tool in cancer research, particularly in studies exploring GST inhibition and its therapeutic implications in oncology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2201798-21-0
Applications GST Inhibitor
Formula C8H4ClNO2S
Molecular Weight 213.64
SMILES
[O-]C1=C(C2=CC=C(Cl)C=C2)[S+]=NO1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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