Fig. 1 · Structure

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OZO-H

GST Inhibitor

OZO-H is a potent inhibitor of glutathione S-transferase (GST) activity. As a derivative of OZO, this compound exhibits significant anti-cancer effects by disrupting the GST-JNK1 complex, leading to the release and subsequent phosphorylation of JNK1. The activation of c-Jun through JNK1 phosphorylation highlights its potential utility in cancer research, particularly in studies examining cell signaling pathways related to tumor progression and therapeutic response.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 60027-35-2
Applications GST Inhibitor
Formula C8H5NO2S
Molecular Weight 179.20
Synonyms CAY10562
SMILES
[O-]C1=C(C2=CC=CC=C2)SN=[O+]1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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