Fig. 1 · Structure
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P-CAB agent 1
P-CAB Agent
P-CAB agent 1 is a highly potent potassium-competitive acid blocker that targets the H+/K+-ATPase with an IC50 value of 60.50 nM. This compound demonstrates satisfactory oral absorption in rodent models. P-CAB agent 1 is utilized in research focusing on acid-related disorders (ARDs), contributing to the understanding of gastric acid secretion and its implications in various gastrointestinal conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 2374139-68-9 |
| Applications | P-CAB Agent |
| Formula | C26H23FN4O |
| Molecular Weight | 426.49 |
| SMILES | O=C(N)C1=CC(C2=CC=CC(CN3N=C4CN(CC4=C3C5=CC=CC=C5F)C)=C2)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.