Fig. 1 · Structure
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p-Cresyl sulfate
Uremic Toxin
p-Cresyl sulfate, a uremic toxin, primarily mediates its effects through renal damage and dysfunction. This compound exhibits antiproliferative activity, enhancing the protein expression of HIF-1α and VHL while reducing HIF-2α levels. Additionally, p-Cresyl sulfate triggers epithelial-mesenchymal transition (EMT) and activates the JNK and p38 MAPK signaling pathways. Its biological activity makes it relevant for research into kidney-related pathologies and cellular signaling mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3233-58-7 |
| Applications | Uremic Toxin |
| Formula | C7H8O4S |
| Molecular Weight | 188.20 |
| Synonyms | p-Tolyl sulfate |
| SMILES | O=S(OC1=CC=C(C)C=C1)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.