p-fin4 is a peptide inhibitor targeting the interaction between STEP phosphatase and the GluA2 subunit of the AMPA receptor, with a Ki of 0.4 μM. This compound has demonstrated the ability to restore memory deficits and exhibits anxiolytic and antidepressant effects in a scopolamine-induced rat model. p-fin4 represents a potential lead for the development of innovative cognitive enhancers and behavioral modulators, highlighting its significance in neurological research.
p-fin4 is a peptide inhibitor targeting the interaction between STEP phosphatase and the GluA2 subunit of the AMPA receptor, with a Ki of 0.4 μM. This compound has demonstrated the ability to restore memory deficits and exhibits anxiolytic and antidepressant effects in a scopolamine-induced rat model. p-fin4 represents a potential lead for the development of innovative cognitive enhancers and behavioral modulators, highlighting its significance in neurological research.
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