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P18IN005 hydrochloride

CDK Inhibitor

P18IN005 hydrochloride is a selective inhibitor of cyclin-dependent kinase (CDK), primarily targeting p18. This compound effectively regulates hematopoietic stem cell (HSC) self-renewal, demonstrating superior potency compared to p27 in mouse models. P18IN005 hydrochloride enhances the expansion of functional HSCs in short-term cultures, making it a valuable reagent for investigating the signaling pathways that govern stem cell self-renewal and differentiation processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	7403-44-3
Applications	CDK Inhibitor
Formula	C₁₉H₂₄ClNO₂
Molecular Weight	333.85
SMILES	COC1=CC=C(C=C1)C(C(C2=CC=CC=C2)NCCCC)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.