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p27

CDK Inhibitor

p27 is a cyclin-dependent kinase (CDK) inhibitor that functions as a substrate for the SCFSkp2/Cks1 complex. This protein plays a crucial role in cell cycle regulation by inhibiting CDK activity, thereby impacting cell proliferation. p27 is widely used in cancer research to investigate the mechanisms of tumorigenesis and to explore therapeutic strategies for targeting cell cycle dysregulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	959369-94-9
Applications	CDK Inhibitor
Formula	C₄₄H₇₈N₁₃O₁₉P
Molecular Weight	1124.14
SMILES	C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](C)N)=O)=O)CO)=O)C(C)C)=O)CCC(O)=O)=O)CCC(N)=O)=O)[C@H](OP(=O)(O)O)C)(=O)N1[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCCN)=O)CCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.