p5 Ligand for Dnak and DnaJ

Catalog No.: A37536
HSP
p5 Ligand for DnaK and DnaJ is a nonapeptide that specifically targets the heat shock proteins DnaK and DnaJ. This ligand corresponds to the primary binding site of a 23-residue segment within the presequence of mitochondrial aspartate aminotransferase, demonstrating high affinity for these chaperones. Its biological activity supports research in cellular stress responses and protein folding mechanisms, making it valuable for studies on molecular chaperones and their roles in various cellular contexts.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionp5 Ligand for DnaK and DnaJ is a nonapeptide that specifically targets the heat shock proteins DnaK and DnaJ. This ligand corresponds to the primary binding site of a 23-residue segment within the presequence of mitochondrial aspartate aminotransferase, demonstrating high affinity for these chaperones. Its biological activity supports research in cellular stress responses and protein folding mechanisms, making it valuable for studies on molecular chaperones and their roles in various cellular contexts.
Product Information
Catalog NumA37536
FormulaC44H81N15O11S
Molecular Weight1028.27
CAS Number209518-24-1
SequenceCys-Leu-Leu-Leu-Ser-Ala-Pro-Arg-Arg
Sequence shorteningCLLLSAPRR
SMILESC(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CS)N)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CO)=O)C)=O)CCC1
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