Fig. 1 · Structure

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P516-0475

PepO Inhibitor, Rgg2/3 Agonist

P516-0475 is an uncompetitive inhibitor of the endopeptidase PepO, targeting bacterial proteolytic processes. Additionally, it acts as an agonist of the Rgg2/3 system, enhancing the expression of Rgg2/3-regulated genes in the presence of short hydrophobic pheromone (SHP). This dual functionality confers antibacterial properties, contributing to increased lysozyme resistance and offering potential applications in microbiological research and the development of antimicrobial strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1359627-33-0
Applications PepO Inhibitor, Rgg2/3 Agonist
Formula C15H17N5O3
Molecular Weight 315.33
SMILES
O=C(C1=C2N(N=N1)C3=C(C=C(C)C=C3)NC2=O)NCCCOC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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