p53 Activator 10

Catalog No.: A53846
p53 Activator
p53 Activator 10 is designed to specifically activate the Y220C mutant form of the p53 tumor suppressor protein. By enhancing p53 activity, this compound plays a crucial role in promoting cell cycle arrest and apoptosis in cancer cells. It is primarily utilized in research focused on understanding the mechanisms of tumor suppression and therapeutic strategies against p53-related malignancies.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionp53 Activator 10 is designed to specifically activate the Y220C mutant form of the p53 tumor suppressor protein. By enhancing p53 activity, this compound plays a crucial role in promoting cell cycle arrest and apoptosis in cancer cells. It is primarily utilized in research focused on understanding the mechanisms of tumor suppression and therapeutic strategies against p53-related malignancies.
Product Information
Catalog NumA53846
FormulaC26H28F3N5O2S
Molecular Weight531.59
CAS Number2849484-29-1
SMILESFC(F)(F)CN1C(C#CCNC2=CC=C(S(NC3)(=O)=O)C3=C2)=CC4=C(NC5CCN(C)CC5)C=CC=C41
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