p53 Activator 3 (compound 87A) is a potent activator of the p53 tumor suppressor protein, demonstrating a SC150 value of less than 0.05 mM. This compound binds to mutant forms of p53, effectively restoring their DNA-binding capability and exhibiting significant anti-tumor activity. Additionally, p53 Activator 3 serves as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules, facilitating diverse biological applications.
p53 Activator 3 (compound 87A) is a potent activator of the p53 tumor suppressor protein, demonstrating a SC150 value of less than 0.05 mM. This compound binds to mutant forms of p53, effectively restoring their DNA-binding capability and exhibiting significant anti-tumor activity. Additionally, p53 Activator 3 serves as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules, facilitating diverse biological applications.
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