p53 Activator 7 is a specialized activator for the p53 mutation Y220C, targeting the MDM2-p53 interaction with an EC50 of 104 nM. This compound enhances the DNA-binding capability of the mutant p53, offering valuable insight into p53 functionality and regulation. Additionally, p53 Activator 7 features a reactive alkyne group, enabling its use as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This characteristic expands its utility in chemical biology and molecular research applications.
p53 Activator 7 is a specialized activator for the p53 mutation Y220C, targeting the MDM2-p53 interaction with an EC50 of 104 nM. This compound enhances the DNA-binding capability of the mutant p53, offering valuable insight into p53 functionality and regulation. Additionally, p53 Activator 7 features a reactive alkyne group, enabling its use as a click chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This characteristic expands its utility in chemical biology and molecular research applications.
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