Fig. 1 · Structure

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p53-Y220C/PLK1 modulator-1

Cat. No. A53850 CAS 3114732-99-6

p53-Y220C/PLK1 Modulator

p53-Y220C/PLK1 modulator-1 is a novel dual modulator targeting the p53-Y220C mutation and Polo-like kinase 1 (PLK1). This compound exhibits significant biological activity in cancer research, providing a potential therapeutic avenue for tumors harboring the p53-Y220C alteration. Its application in cellular and molecular studies can facilitate the exploration of p53-mediated pathways and PLK1 functionality in oncogenesis.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 3114732-99-6
Applications p53-Y220C/PLK1 Modulator
Formula C60H77ClN10O12S
Molecular Weight 1197.83
SMILES
CC[C@@H]1C(N(C2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(C=C4OC)C(NCCOCCOCCOCCOCCC(N5CCC(CC5)NC6=CC=CC7=C6C(C)=C(N7C(CCl)=O)C#CCNC8=C(C=C(C=C8)S(C)(=O)=O)OC)=O)=O)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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