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- Oku H, .et al. P7C3 Suppresses Neuroinflammation and Protects Retinal Ganglion Cells of Rats from Optic Nerve Crush, Invest Ophthalmol Vis Sci, 2017, Sep 1;58(11):4877-4888 PMID: 28973334
- Oku H, .et al. Protective effect of P7C3 on retinal ganglion cells from optic nerve injury, Jpn J Ophthalmol, 2017, Mar;61(2):195-203 PMID: 28032230
Biological Activity
P7C3-A20 is a potent neuroprotective agent.
| In vitro | DMSO | 96 mg/mL (189.64 mM) | |
| Water | <1 mg/mL | ||
| Ethanol | <1 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.75 mL | 98.77 mL | 197.55 mL |
| 0.5 mM | 3.95 mL | 19.75 mL | 39.51 mL |
| 1 mM | 1.98 mL | 9.88 mL | 19.75 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.95 mL |
*The above data is based on the productmolecular weight 506.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12581 |
|---|---|
| Actions | Activator |
| CAS No. | 1235481-90-9 |
| Formula | C22H19Br2FN2O |
| M. Wt | 506.21 |
| Purity | >98% |
| Synonyms | P7C3A20 |
| SMILES | COC1=CC=CC(=C1)NCC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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