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PACA

Neuroprotective Agent

PACA is a neuroprotective agent that enhances nerve growth factor (NGF)-induced neurite outgrowth and mitigates neurotoxicity caused by 6-hydroxydopamine (6-OHDA) through activation of the Nrf2/HO-1 pathway. This compound exhibits significant neuroprotective and neurogenic properties, making it valuable for research focused on dopaminergic neuron degeneration. PACA has potential applications in studying motor dysfunction and neuronal loss in Parkinson's disease models, including MPTP mice and MPP+-exposed neurons.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1431724-30-9
Applications	Neuroprotective Agent
Formula	C₁₂H₁₁NO₃
Molecular Weight	217.22
SMILES	O=C(/C=C/C1=CC=C(C(O)=C1)O)NCC#C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.