Fig. 1 · Structure
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PACAP (6-27) (human, ovine, rat)
PACAP Receptor Antagonist
PACAP (6-27) is a potent PACAP receptor antagonist that inhibits the response of canine adrenal catecholamines to exogenous vasoactive intestinal peptide (VIP). This compound is instrumental for studying the underlying mechanisms in cardiovascular and neurological diseases, facilitating research into therapeutic strategies targeting PACAP signaling pathways. Its applicability spans across human, ovine, and rat models, making it a versatile tool in biomedical research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 136134-68-4 |
| Applications | PACAP Receptor Antagonist |
| Formula | C121H193N33O31S |
| Molecular Weight | 2638.09 |
| Synonyms | Pituitary adenylate cyclase-activating peptide (6-27) |
| SMILES | [C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)[C@@H](C)C)=O)C)=O)C)=O)CC(C)C)=O)=O)CCCCN)=O)CCCCN)=O)C(C)C)=O)C)=O)CCSC)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)N)=O)[C@@H](C)O)=O)CC(O)=O)=O)CO)=O)=O)CO)=O)CCCNC(=N)N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.