Fig. 1 · Structure
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PACAP (6-38), human, ovine, rat
PACAP Receptor Antagonist
PACAP (6-38) is a potent antagonist of PACAP receptors, exhibiting IC50 values of 30 nM, 600 nM, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively. This compound effectively disrupts PACAP signaling pathways, making it a valuable tool for research into neuropeptide functions and their roles in various physiological processes. It is applicable in studies focusing on the modulation of neuroprotection, stress response, and neuroinflammatory conditions in both human and animal models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 143748-18-9 |
| Applications | PACAP Receptor Antagonist |
| Formula | C182H300N56O45S |
| Molecular Weight | 4024.74 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.