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Paclitaxel-maleimide

Paclitaxel Modified With Maleimide

Paclitaxel-maleimide is a conjugate of paclitaxel modified with a maleimide linker, designed to enhance binding interactions. This compound demonstrates significant binding affinity for bovine serum albumin (BSA), making it a valuable tool in pharmacokinetic studies. Paclitaxel-maleimide is particularly applicable in tumor research, facilitating the investigation of drug delivery systems and targeted therapies in oncology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	254893-84-0
Applications	Paclitaxel Modified With Maleimide
Formula	C₅₄H₅₆N₂O₁₇
Molecular Weight	1005.03
SMILES	CC(O[C@]12[C@@]3([H])[C@@H]([C@]4(C(C)(C([C@H](C([C@@]3([C@H](C[C@@]1([H])OC2)O)C)=O)OC(C)=O)=C([C@H](C4)OC([C@H](OC(CCN5C(C=CC5=O)=O)=O)[C@H](C6=CC=CC=C6)NC(C7=CC=CC=C7)=O)=O)C)C)O)OC(C8=CC=CC=C8)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.