Fig. 1 · Structure

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Paclitaxel-MVCP

Drug-Linker Conjugate

Paclitaxel-MVCP (MC-Val-Cit-PAB-Paclitaxel) is a drug-linker conjugate designed for targeted drug delivery applications. This compound enables the synthesis of Paclitaxel-nucleolin aptamer conjugates, facilitating selective cytotoxicity in cancer cells. Its primary mechanism of action involves the release of Paclitaxel upon cellular uptake, enhancing therapeutic efficiency in oncology research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2119034-12-5
Applications Drug-Linker Conjugate
Formula C76H89N7O22
Molecular Weight 1452.55
Synonyms MC-Val-Cit-PAB-Paclitaxel
SMILES
O=C(C1=CC=CC=C1)N[C@@H](C2=CC=CC=C2)[C@H](C(O[C@@H]3C(C)=C([C@@H](OC(C)=O)C([C@@]4(C)[C@]([C@@](CO5)(OC(C)=O)[C@@]5([H])C[C@@H]4O)([H])[C@@H]6OC(C7=CC=CC=C7)=O)=O)C(C)(C)[C@@]6(O)C3)=O)OC(OCC(C=C8)=CC=C8NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN9C(C=CC9=O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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