Palbociclib-d4 is a stable isotope-labeled form of Palbociclib, a selective inhibitor of CDK4 and CDK6, demonstrating IC50 values of 11 and 16 nM respectively. This compound exhibits strong anti-proliferative effects and effectively induces cell cycle arrest in cancer cells. Palbociclib-d4 is primarily utilized in research related to hormone receptor-positive and HER2-negative breast cancer, as well as hepatocellular carcinoma studies.
Palbociclib-d4 is a stable isotope-labeled form of Palbociclib, a selective inhibitor of CDK4 and CDK6, demonstrating IC50 values of 11 and 16 nM respectively. This compound exhibits strong anti-proliferative effects and effectively induces cell cycle arrest in cancer cells. Palbociclib-d4 is primarily utilized in research related to hormone receptor-positive and HER2-negative breast cancer, as well as hepatocellular carcinoma studies.
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