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Paltimatrectinib

Catalog No.: A34978
Tyrosine Kinase Inhibitor
Paltimatrectinib is a potent tyrosine kinase inhibitor with an IC50 of less than 10 nM for tropomyosin receptor kinases A (TrkA). This compound demonstrates significant biological activity in inhibiting cell proliferation and migration associated with cancer and inflammatory diseases. Paltimatrectinib is applicable in research focused on therapeutic strategies for malignancies and inflammatory disorders.
Paltimatrectinib 2353522-15-1 Tyrosine Kinase Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$160.00
In stock
5mg
$285.00
In stock
10mg
$505.00
In stock
25mg
$1,050.00
In stock
50mg
$1,600.00
In stock
100mg
$2,560.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPaltimatrectinib is a potent tyrosine kinase inhibitor with an IC50 of less than 10 nM for tropomyosin receptor kinases A (TrkA). This compound demonstrates significant biological activity in inhibiting cell proliferation and migration associated with cancer and inflammatory diseases. Paltimatrectinib is applicable in research focused on therapeutic strategies for malignancies and inflammatory disorders.
Product Information
Catalog NumA34978
FormulaC20H15F5N6
Molecular Weight434.37
CAS Number2353522-15-1
SMILESFC(F)(C1=CN(N=C1)C2=C3N(C=CC(N4[C@](C5=C(C=CC(F)=C5)F)([H])CCC4)=N3)N=C2)F
SynonymsPBI-200; PPI-5278
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Protein Tyrosine Kinases > Trk Receptors