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PAMAM dendrimer G0.5 carboxylate sodium (8.78% w/w in water)

PAMAM Dendrimer

PAMAM Dendrimer G0.5 Carboxylate Sodium is a polyamidoamine dendrimer featuring carboxylate termini, designed for biomedical applications. This dendrimer exhibits notable cytotoxicity against various cancer cell lines, including A2780 ovarian cancer cells, MCF-7 breast cancer cells, Caco-2 colon cancer cells, and BJ fibroblasts, with IC50 values of 0.03 µM, 1.6 µM, 0.18 µM, and 3 µM, respectively. Its remarkable drug delivery potential and biocompatibility make it suitable for targeted therapy and nanomedicine research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	339334-01-9
Applications	PAMAM Dendrimer
Formula	C₄₆H₇₂N₁₀Na₈O₂₀
Molecular Weight	1269.04
SMILES	O=C(CCN(CCC(O[Na])=O)CCNC(CCN(CCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)O[Na]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.