Fig. 1 · Structure

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PAMAM dendrimer G1.5 carboxylate sodium

MERS‐CoV Inhibitor

PAMAM dendrimer G1.5 carboxylate sodium is a polyanionic dendrimer that functions as an inhibitor of MERS-CoV by interfering with viral entry or replication. This compound exhibits notable antiviral activity, demonstrating a 40.5% inhibition rate in viral plaque assays. It serves as a valuable tool for research aimed at understanding and combating MERS-CoV infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 251970-28-2
Applications MERS‐CoV Inhibitor
Formula C110H176N26Na16O44
Molecular Weight 2934.56
Synonyms PAMAM G1.5 carboxylate sodium
SMILES
O=C(CCN(CCC(O[Na])=O)CCNC(CCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCNC(CCN(CCN(CCC(NCCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)CCC(NCCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)CCC(NCCN(CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)CCC(NCCN(CCC(O[Na])=O)CCC(O[Na])=O)=O)=O)=O)=O)O[Na]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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