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Panobinostat-d4

Stable Isotope

Panobinostat-d4 is a deuterium-labeled derivative of Panobinostat, a potent non-selective histone deacetylase (HDAC) inhibitor with significant antineoplastic properties. This compound effectively induces HIV-1 production in latently infected cells at low concentrations, enhancing viral expression and facilitating studies on HIV latency. Additionally, Panobinostat promotes apoptosis and autophagy in cancer cells, making it valuable for research on refractory or relapsed multiple myeloma.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1185237-51-7
Applications	Stable Isotope
Formula	C₂₁H₁₉D₄N₃O₂
Molecular Weight	353.45
Synonyms	LBH589-d4; NVP-LBH589-d4
SMILES	O=C(NO)/C=C/C1=CC=C(CNCCC2=C(C)NC3=C2C([2H])=C([2H])C([2H])=C3[2H])C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.