Fig. 1 · Structure
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Pantothenate kinase-IN-1
PANK3 Inhibitor
Pantothenate kinase-IN-1 is a selective inhibitor of PANK3, exhibiting an IC50 value of 0.51 μM. By competing with pantothenate for the binding site, this compound effectively inhibits PANK3 dimers and is stable in mouse and rat plasma. Pantothenate kinase-IN-1 is valuable in the study of pantothenate kinase-related neurodegenerative and metabolic disorders. This reagent offers a potent tool for advancing research in cellular metabolism and related disease mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1024168-48-6 |
| Applications | PANK3 Inhibitor |
| Formula | C21H25N5O |
| Molecular Weight | 363.46 |
| SMILES | CC(C)(C1=CC=C(C=C1)NC(N2CCN(CC2)C3=NC=C(C=C3)C#N)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.