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PAR4 antagonist 3

PAR4 Inhibitor

PAR4 antagonist 3 is a selective inhibitor of protease-activated receptor 4 (PAR4). This compound demonstrates significant antiplatelet activity, with an IC50 value of 26.1 nM, making it a valuable tool for studies related to thrombosis and platelet function. Additionally, PAR4 antagonist 3 shows improved metabolic stability in human liver microsomes, with a half-life of 97.6 minutes, enhancing its potential for in vivo applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3057206-40-0
Applications	PAR4 Inhibitor
Formula	C₂₂H₁₆FN₃O₅S
Molecular Weight	453.44
SMILES	FC1=CC=C(OCC2COC3=CC=C4C(OC(C5=CN6C(SC(OC)=N6)=N5)=C4)=C3O2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.