Fig. 1 · Structure

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Paracetamol-cysteine

Paracetamol protein adduct

Paracetamol-cysteine is a protein adduct formed from the conjugation of paracetamol with cysteine through the reactive metabolite N-acetyl-p-benzoquinoneimine (NAPQI). This compound is significant in studies related to paracetamol-induced hepatotoxicity, serving as a biomarker for acetaminophen overdose and oxidative stress. Research applications include investigations into drug metabolism, toxicity assessment, and studies of intervention strategies for mitigating liver damage.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 53446-10-9
Applications Paracetamol protein adduct
Formula C11H14N2O4S
Molecular Weight 270.30
Synonyms APAP-Cys

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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