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Pardaxin P 4

Catalog No.: A48806
Antimicrobial Peptide
Pardaxin P 4 is an antimicrobial peptide that targets and interacts with biomembranes. It exhibits a unique mechanism of inducing cytotoxicity and pore formation by disrupting phospholipid bilayers of varying compositions. This peptide is valuable for research applications focused on developing antimicrobial drugs and exploring membrane-disruptive mechanisms in microbial defense.
Pardaxin P 4 134940-98-0 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPardaxin P 4 is an antimicrobial peptide that targets and interacts with biomembranes. It exhibits a unique mechanism of inducing cytotoxicity and pore formation by disrupting phospholipid bilayers of varying compositions. This peptide is valuable for research applications focused on developing antimicrobial drugs and exploring membrane-disruptive mechanisms in microbial defense.
Product Information
Catalog NumA48806
FormulaC154H248N36O45
Molecular Weight3323.83
CAS Number134940-98-0
SequenceGly-Phe-Phe-Ala-Leu-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Leu-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Gly-Gln-Glu
Sequence shorteningGFFALIPKIISSPLFKTLLSAVGSALSSSGGQE
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CC=CC=C2)NC(CN)=O)=O)=O)C)=O)CC(C)C)=O)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CCC(N)=O)=O)=O)=O)CO)=O)CO)=O)CO)=O)CC(C)C)=O)C)=O)CO)=O)=O)C(C)C)=O)C)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)[C@@H](C)O)=O)CCCCN)=O)=O)CC(C)C)=O)CCC4)CO)=O)CO)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)CCC3
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