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Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.06 mL | 65.28 mL | 130.57 mL |
| 0.5 mM | 2.61 mL | 13.06 mL | 26.11 mL |
| 1 mM | 1.31 mL | 6.53 mL | 13.06 mL |
| 5 mM | 0.26 mL | 1.31 mL | 2.61 mL |
*The above data is based on the productmolecular weight 765.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17625 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 765.88 |
| Formula | C40H43N7O7S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1216941-48-8 |
| Synonyms | ATB450; ABT-450; ABT 450; Paritaprevir; Veruprevir; Brand name: VIEKIRA PAK. |
| SMILES | O=C([[email protected]]([[email protected]]1([H])/C=C\CCCCC[[email protected]@H]2NC(C3=NC=C(C)N=C3)=O)(C1)NC([[email protected]@](C[[email protected]@H](OC4=C5C=CC=CC5=C(C=CC=C6)C6=N4)C7)([H])N7C2=O)=O)NS(=O)(C8CC8)=O |
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