Paritaprevir (ABT-450)

Catalog No.: A17625

HCV NS3/4A inhibitor

Paritaprevir (ABT-450)

Paritaprevir (ABT-450) Chemical Structure

CAS NO. 1216941-48-8

Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively.

Availability: In stock

Package Price Qty
5 mg
$140.00
10 mg
$200.00
50 mg
$580.00
100 mg
$1,080.00
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Biological Activity

Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively.
In vitro DMSO 97 mg/mL (126.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.06 mL 65.28 mL 130.57 mL
0.5 mM 2.61 mL 13.06 mL 26.11 mL
1 mM 1.31 mL 6.53 mL 13.06 mL
5 mM 0.26 mL 1.31 mL 2.61 mL

*The above data is based on the productmolecular weight 765.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17625
Actions Inhibitor
CAS No. 1216941-48-8
Formula C40H43N7O7S
M. Wt 765.88
Purity >98%
Synonyms ATB450; ABT-450; ABT 450; Paritaprevir; Veruprevir; Brand name: VIEKIRA PAK.
SMILES O=C([[email protected]]([[email protected]]1([H])/C=C\CCCCC[[email protected]@H]2NC(C3=NC=C(C)N=C3)=O)(C1)NC([[email protected]@](C[[email protected]@H](OC4=C5C=CC=CC5=C(C=CC=C6)C6=N4)C7)([H])N7C2=O)=O)NS(=O)(C8CC8)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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