Paroxetine-d4

Catalog No.: A32970
Stable Isotope
Paroxetine-d4 is a deuterium-labeled derivative of Paroxetine, a selective serotonin reuptake inhibitor (SSRI). This compound is primarily utilized in research to study the pharmacokinetics and metabolic pathways of SSRIs. Known for its antidepressant and anxiolytic properties, Paroxetine also exhibits weak norepinephrine reuptake inhibition, which can induce apoptosis in certain cell types and has been associated with anti-tumor activity. Research applications include investigations into psychiatric disorders such as obsessive-compulsive disorder, panic disorder, and post-traumatic stress disorder, as well as the management of chronic pain conditions.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionParoxetine-d4 is a deuterium-labeled derivative of Paroxetine, a selective serotonin reuptake inhibitor (SSRI). This compound is primarily utilized in research to study the pharmacokinetics and metabolic pathways of SSRIs. Known for its antidepressant and anxiolytic properties, Paroxetine also exhibits weak norepinephrine reuptake inhibition, which can induce apoptosis in certain cell types and has been associated with anti-tumor activity. Research applications include investigations into psychiatric disorders such as obsessive-compulsive disorder, panic disorder, and post-traumatic stress disorder, as well as the management of chronic pain conditions.
Product Information
Catalog NumA32970
FormulaC19H16D4FNO3
Molecular Weight333.39
CAS Number923932-45-0
SMILES[2H]C1([2H])OC2=CC=C(C=C2O1)OC([2H])([2H])[C@H]3[C@H](C4=CC=C(C=C4)F)CCNC3
SynonymsBRL29060-d4
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