Fig. 1 · Structure
Documents & Downloads
PARP-1/2/7-IN-1
PARP1/2/7 Inhibitor
PARP-1/2/7-IN-1 is a highly potent inhibitor of poly (ADP-ribose) polymerases PARP-1, PARP-2, and PARP-7, demonstrating an IC50 of less than 10 nM. This compound is valuable for research applications focused on cancer biology, DNA repair mechanisms, and cellular stress responses. Its multifunctional inhibition can aid in the exploration of therapeutic strategies targeting PARP-mediated pathways in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3034665-49-8 |
| Applications | PARP1/2/7 Inhibitor |
| Formula | C22H23F6N7O3 |
| Molecular Weight | 547.45 |
| SMILES | O=C1NN=C2C(CC[C@H]2N3C[C@H](C(N4CCN(C5=NC=C(C(F)(F)F)C=N5)CC4)=O)OCC3)=C1C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.