Fig. 1 · Structure

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PARP-1/2-IN-5

PARP-1/2 Inhibitor

PARP-1/2-IN-5 is a potent inhibitor of PARP-1 and PARP-2, with IC50 values of 118 nM and 11 nM, respectively. This compound is ideal for investigating its role in inflammatory diseases and neurodegenerative disorders, providing valuable insights into the therapeutic potential of PARP inhibition in these conditions. Researchers can utilize PARP-1/2-IN-5 to explore the molecular mechanisms underlying these diseases and assess potential treatment strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 489457-75-2
Applications PARP-1/2 Inhibitor
Formula C16H10F3N3O
Molecular Weight 317.27
SMILES
O=C(C1=C2N=C(C3=CC=C(C(F)(F)F)C=C3)C=NC2=CC=C1)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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