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PARP1/2-IN-4

PARP1/2 Inhibitor

PARP1/2-IN-4 is a selective inhibitor of PARP1 and PARP2 enzymes, which play crucial roles in DNA repair processes via the base excision repair pathway. This compound exhibits significant potential in preclinical research for cancer therapy by enhancing the efficacy of DNA-damaging agents and promoting synthetic lethality in tumors with deficient DNA repair mechanisms. It is a valuable tool for studying DNA repair pathways and evaluating therapeutic strategies in oncology research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2093102-22-6
Applications	PARP1/2 Inhibitor
Formula	C₂₃H₃₀FN₅O₆
Molecular Weight	491.51
SMILES	FC1=CC(C(N)=O)=C2C(NC3=C(C4(C)CCN(C(C)C)CC4)C=NN32)=C1.OC(/C=C\C(O)=O)=O.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.