Fig. 1 · Structure
Documents & Downloads
PARP1-IN-31
PARP1-IN-31 is a phthalazinone derivative that functions as a potent inhibitor of poly (ADP-ribose) polymerase 1 (PARP-1), exhibiting an IC50 of 97 nM. It demonstrates significant anti-proliferative effects and induces apoptosis in lung adenocarcinoma cell lines. This compound serves as a valuable tool for research investigating PARP-1-mediated pathways in cancer biology and therapeutic strategies targeting lung cancer.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 684234-60-4 |
| Formula | C22H15ClFN3O2 |
| Molecular Weight | 407.82 |
| SMILES | O=C(NC1=CC=C(F)C=C1)CN(N=C(C2=CC=C(Cl)C=C2)C3=C4C=CC=C3)C4=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.