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PARP1-IN-36

PARP1 Inhibitor

PARP1-IN-36 is a selective inhibitor of PARP-1, characterized as a 4-carboxamido-isoindolinone derivative with a Kd value of less than 0.01 μM. This compound exhibits significant biological activity in the modulation of cellular processes associated with DNA repair, making it a valuable tool in research focused on cancer, cardiovascular diseases, nervous system injury, and inflammation. Its potent inhibition of PARP-1 serves to elucidate the role of this enzyme in various pathological contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1606996-12-6
Applications	PARP1 Inhibitor
Formula	C₂₀H₂₇N₃O₂
Molecular Weight	341.45
SMILES	O=C(C1=CC=CC2=C1C(N(C3CCN(C4CCCCC4)CC3)C2)=O)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.