PARP1-IN-36 is a selective inhibitor of PARP-1, characterized as a 4-carboxamido-isoindolinone derivative with a Kd value of less than 0.01 μM. This compound exhibits significant biological activity in the modulation of cellular processes associated with DNA repair, making it a valuable tool in research focused on cancer, cardiovascular diseases, nervous system injury, and inflammation. Its potent inhibition of PARP-1 serves to elucidate the role of this enzyme in various pathological contexts.
PARP1-IN-36 is a selective inhibitor of PARP-1, characterized as a 4-carboxamido-isoindolinone derivative with a Kd value of less than 0.01 μM. This compound exhibits significant biological activity in the modulation of cellular processes associated with DNA repair, making it a valuable tool in research focused on cancer, cardiovascular diseases, nervous system injury, and inflammation. Its potent inhibition of PARP-1 serves to elucidate the role of this enzyme in various pathological contexts.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
