PARP1-IN-37 is a selective inhibitor of poly(ADP-ribose) polymerases 1 and 2 (PARP1/2), exhibiting an IC50 of 24 nM for PARP1. This compound effectively inhibits PARP activity in cellular assays with an EC50 of 3.7 μM. PARP1-IN-37 is particularly relevant for investigations into BRCA-mutated tumors, including breast and ovarian cancers, making it a valuable tool for cancer research and therapeutic development.
PARP1-IN-37 is a selective inhibitor of poly(ADP-ribose) polymerases 1 and 2 (PARP1/2), exhibiting an IC50 of 24 nM for PARP1. This compound effectively inhibits PARP activity in cellular assays with an EC50 of 3.7 μM. PARP1-IN-37 is particularly relevant for investigations into BRCA-mutated tumors, including breast and ovarian cancers, making it a valuable tool for cancer research and therapeutic development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
