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PARP1-IN-48

PARP1 Inhibitor

PARP1-IN-48 is a potent and selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1), exhibiting an IC50 of 3 nM against PARP1 and 170 nM against PARP2. This compound is valuable for research in oncology, virology, and metabolic disorders, facilitating investigations into the role of PARP1 in DNA repair and cellular stress responses. Its selective action makes it an essential tool for studying therapeutic pathways in cancer treatment and other disease models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3085256-81-8
Applications	PARP1 Inhibitor
Formula	C₁₈H₂₄N₄OS
Molecular Weight	344.47
SMILES	CCC(N1CCN(CC1)CC2=CC3=C(N=C2)C=C(C(N3)=O)CC)=S

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.