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PARP1-IN-54

PARP1 Inhibitor

PARP1-IN-54 is a selective inhibitor of the poly(ADP-ribose) polymerase 1 (PARP1) enzyme, which plays a crucial role in DNA repair mechanisms. This compound exhibits significant antitumor activity, making it a valuable tool in cancer research. Its inhibition of PARP1 can effectively enhance the therapeutic efficacy of DNA-damaging agents, and it is particularly relevant in studies focusing on cancer biology and treatment strategies involving synthetic lethality.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2915309-47-4
Applications	PARP1 Inhibitor
Formula	C₂₃H₂₄FN₇O₂
Molecular Weight	449.48
SMILES	CC1=NC(C(NC)=O)=CC=C1N2CCN(CC2)CC3=CC(F)=C4N5C(C(NC4=C3)=O)=CC=N5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.