Fig. 1 · Structure
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PARP1-IN-56
PARP1 Inhibitor
PARP1-IN-56 is a potent inhibitor of poly(ADP-ribose) polymerase 1 (PARP1), a key enzyme involved in DNA repair mechanisms. This compound can be radiolabeled with isotopes such as 211At or 125I, facilitating its application as an α-emitting radiotherapeutic agent in oncological research. PARP1-IN-56 has significant potential for studying cancer therapy by targeting PARP1's role in tumor survival and proliferation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1574367-80-8 |
| Applications | PARP1 Inhibitor |
| Formula | C16H12IN3O |
| Molecular Weight | 389.19 |
| SMILES | O=C1NCCN2C(C3=CC=C(I)C=C3)=NC4=CC=CC1=C42 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.