Fig. 1 · Structure
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PARP1-IN-6
PARP Inhibitor
PARP1-IN-6 is a dual inhibitor of tubulin and PARP-1, displaying IC50 values of 0.94 μM and 0.48 μM, respectively. This compound demonstrates significant biological activity by disrupting cellular processes mediated by both targets, making it a valuable tool for cancer research. PARP1-IN-6 is particularly useful in studies investigating the roles of PARP inhibition in DNA repair mechanisms and cytoskeletal dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1654735-36-0 |
| Applications | PARP Inhibitor |
| Formula | C16H11FN2O |
| Molecular Weight | 266.27 |
| SMILES | O=C1C2=CC=CC=C2N=C(/C=C/C3=CC(F)=CC=C3)N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.