Fig. 1 · Structure
Documents & Downloads
PARP1-IN-7
PARP Inhibitor
PARP1-IN-7 is a selective inhibitor of poly(ADP-ribose) polymerase-1 (PARP1), primarily functioning to disrupt DNA repair mechanisms in cancer cells. By inhibiting PARP1 activity, it enhances the cytotoxic effects of DNA-damaging agents, making it a valuable tool in cancer research. Its applications include studying mechanisms of tumorigenesis, evaluating synthetic lethality in cancer therapies, and exploring potential combinations with other anticancer agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2084112-75-2 |
| Applications | PARP Inhibitor |
| Formula | C24H23N5O |
| Molecular Weight | 397.47 |
| SMILES | N#CC1=CC=C(N2CCN([C@H]3C=C(C4=CC5=C(C(N4)=O)C=CC=N5)CC3)CC2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.